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  1. funsharer

    Rupture Disc for Hot WFI storage tank

    Greg, Thank you for your kind advise. I think you got a point. However, I am still concerned that the WFI storage & distribution system has Ambient water returning from use points and it could cause a full vacuum in a way. It is designed for full vacuum , but we don't want to expose it to...
  2. funsharer

    Rupture Disc for Hot WFI storage tank

    We will install a rupture disc(single acting, positive only) on a Hot WFI storage tank. The tank was manufactured according to ASME code and is designed for full vacuum and equipped with a vent filter ( 30" x 3 poles on 2" nozzle). We will use the tank for hot water application only. I...
  3. funsharer

    FLOWMETER IN HOT WFI DISTRIBUTION LOOP

    I read from ISPE guide book that 3ft/sec is ideal flowspeed in PW or WFI distribution system. I guess we need a sanitary mass flow meter or turbine one to validate the speed. Is it a must to have those instruments to validate the speed? or Can we do it by pressure gauge? Please advise...
  4. funsharer

    PRETREATMENT FOR VAPOR COMPRESSION STILL

    Thank you , Quark & Gary. For your reference, it is not a MES( multi effect still), but vepor compression still made by Acuachem in US. My concern is whether we need a prefilter(5micron) in between ACF & the storage tank when the water quality is good. I am aware that there are pros and cons...
  5. funsharer

    PRETREATMENT FOR VAPOR COMPRESSION STILL

    I 'M A SYSTEM ENGINEER WORKING WITH A BIOPHAM COMPANY. OUR WATER TREATMENT SYSTEM IS UNDER CONSTRUCTION LIKE BELOW; CITY WATER(QUITE QOOD)--> SOFTENER(DUAL) --> STORAGE TANK ---> AC FILTER(DUAL) ---> VAPOR COMPRESSION STILL(ACUACAM) ----> HWFI STORAGE TANK I BELIEVE IT IS A GOOD IDEA TO PUT A...
  6. funsharer

    FAT procedure for hygienic vessels

    Quark, thank you for your kind reply and it sure will help me to do the job. I read some of your advises in some other forums and know you are very active here, which is nice. Your reply have me come up with a question , when we add FAT report and vendor prints to validation documentation, which...
  7. funsharer

    FAT procedure for hygienic vessels

    Hi, I am an engineer working for a biopharmaceutial company and will visit our vessel vendors for FAT. What would be the proper FAT procedure for hygienic vessels? Please help me with this. One more question is which vessels we should go thru. CIP validation test procedure(using spray ball)...

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