Whenever we have moulded thicker sections, we go as low as we can circa 135-140 Deg C actual mould temperature but it does depend on the material you are moulding and when the cure starts to kick in.
We always go for low temperature and long cure time (like baking a big cake) although again...
On thick section rubber moulded parts, you need time for the gases ( given off during heating/curing) to build as the rubber takes heat from the hot mould. Don`t forget rubber is a good insulator so even if you pre-warm the rubber, the mould temperature will still take time to penetrate the...