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Also, if you look at a Moody diagram you'll see that Moody friction factor decreases with an increase in Reynolds number. How does this all relate to design and pressure drop?

I am wondering what the best diameter of pipe is for a given volume flow rate. I understand that conductors are sized based on flow velocity, surface roughness etc. but I have read that fluid friction is reduced at the point of transition from laminar to turbulent...Is there a critical velocity...