I am running dual 24" monitors with an fx3500 at work and dual 22" monitors running off two fx4600s (one plugged into each card) at home and neither have any issues with solidworks 2010 sp2.1 on windows 7. Well except for the occasional black view port issue but I don't believe that is related...
One thing you might want to try to see if it is solidworks or your printer driver is to save your drawing to a pdf and then print the pdf. Alternatively, you could also save it as an e-drawing and try printing from there...
I was having this problem at one point and if I recall correctly, I found a checkbox that said something along the lines of "scale and rotate to fit page" and that did the trick.