I used to be the Construction Estimator/Expeditor for a steel fabricator. I currently am performing structural engineering for an architectural firm.
I contacted the primary supplier when I worked for the fabricator, and inquired what I should be specifying for rolled, wide-flange, structural steel if I want to use Grade 50? I was told to specify A992/Grade 50.
My experience when purchasing for the fabricator was that there was absolutely NO cost difference, to speak of, between Grade 50 and A36. (This is not to say that one should specify Grade 50 exclusively. My reason for stating this is that it has been brought to my attention that there ARE structural situations where we should NOT specify Grade 50. I cannot elaborate on this, as this is something I, also, need to research at this time. I recommend the same.)
Furthermore, I recall one project for which I had sold A36 steel, as specified. The engineer had discovered later, when the WF steel columns had been already delivered to site, that the A36 spec should have been Grade 50. I requested mill tests from the steel supplier for those particular pieces. Fortunately, for the engineer, as craigory28 had suggested, the A36 test results came "close enough" to satisfy the imposed calculated load. "Close enough" was more specifically in the neighborhood or 46-48 ksi. Thus, never assume the A36 WILL be ALL of 50 ksi.
Hope this helps ...