What two wires are you clamping on to? Hots? Neutrals? On the same circuit? Are you clamping on to them at the same time, or individually? What are they feeding? Is this a 2-wire or 3-wire circuit?
Usually, you should only be clamping around one wire at a time. On a 2-wire circuit, the measurement at each wire should be equal, unless there's a ground current. On three-wire circuits, the reading taken on one wire should equal the reading taken by simultaneously clamping onto the other two wires, unless there's a ground fault.
Simultaneously clamping onto all wires in a circuit should read zero unless there is a ground fault. Simultaneously clamping all wires including ground conductor should equal zero unless there's some other unintentional circuit connection.