It can be done but not recommended. If you have a couple of fixtures here and there, not a big deal. However when you are talking a large number of fixtures (over 10-20), it becomes a real issue for the installer/contractor.
Also, more importantly, is there physical room for everything that is going in the block? Not only piping. Are there wall mounted fixtures with floor mounted carriers? If so, a chase is required to have room for the carrier.
Explain this to the architect. A responsible architect will agree to providing adequate space if this means a better quality design. Make sure you know how much space is required and inform or rather (provide consult)for the architect. Your job is to tell the architect what is required for certain fixtures and configurations. If something won't work, it won't work. If it can, it can. If it is not ideal, it's not ideal. Know the difference and be clear in communicating it. Quality designs do not have piping routed in block, but it is allowed and possible.