An alternative to the Taylor Forge method is to treat the flange as a beam on an elastic foundation using formulas in Roark's. Use the gasket stiffness as the foundation stiffness. 2a+t can give awfully close spacing for thin plate flanges, and with 2a + 6t/(m+.5) you have to worry about someone bending the flange during seating if they crank down too hard on the bolts. If you do the beam calc, you can get the foundation stress at the mid-point between bolts. With a thin flange and wide bolt spacing, it will go into tension. Optimize the bolt size, spacing, and flange thickness to keep the gasket stress suitably uniform and the bending stress in the flange below your design limit. When you check the bending in the flange at the bolt location, subtract the hole area before calculating the section modulus.
Depending on your gasket, you might also just treat it as a beam under uniform load, assume the gasket reaction load is constant and limit the beam deflection to some fraction of your total gasket compression.
Both of these ignore the stiffening effect of the hub. Depending on your geometry the hub can help considerably.
If there is any pressure or other loads transmitted through the hub, or if the gasket sits inside the bolts rather than on both sides, you'll need to look at bending across the width of the flange and into the hub as well.
-mskds545