Both will (as indicated) be OK in general. 'Best' will, as always, be depending on a multitude of all relevant details: type of valve(globe, gate, knifegate, ball, check, control etc), size and pressure, temperature limits, detailed construction, precision in machining, type of sealing (seat or body), frequency in operating and so forth, quality of sealing material (EPDM is not always quality EPDM).
General: PTFE if additives present not compatible with EPDM
PTFE if temperature near limits for EPDM.
(General questions without details will produce fewer and general answers)
I'll go into more detail: I'm selecting ball, gate and globe valves for chilled water 5 to 13 degrees C pressure 10 bar. Is that enough to get a specific answer or do you need more data?
