What are you trying to accomplish? If, for example, you are talking about bus differential, a low impedance scheme will allow you to share CT's with other devices. For line & bus protection, dissimilar ratios, types, classes of CT's can be accomodated fairly easily. This assumes the use of a modern digital relay.
High Impedance bus differential "sums" all of the CT's, preferrably to a marshalling or summation box. There are partial differential schemes where 2 sets of CT's are used with an overcurrent relay. The drawbacks of the High impedance scheme is the requirement of dedicated CT's with the same ratio and accuracy classifications. There are workarounds if multi-ratio CT's or Aux CT's are used. I recall a discussion on this forum about a "summation CT", and this may be very different from what is mentioned above. I haven't seen a "summation CT" utilized in my neck of the woods.