The back lash will depend upon the fit, form function of the gear train, Dudleys Gear Handbook has recommended Backlash allowance for power gearing , Page 5-37 , Table 5-11.
the Min & Max center distance according to Dudley is the following.
the stackup of center distance mounting bores, the thickness of the teeth, The pitch diameter runout.
from my experience the the machine tolerances of the housing mounting bores,the mounting shafts, and the precision of the gears will affect alignment.
in other words the application will dictate the precision required to maintain the all of the above requirements.
and it must be designed and machined up front, and must be inspected accordinly. so it's more than just backlash,
it the overall attributes of the gears train.
not a so simple answer:/