jbr549,
In addition to paying close attention to the superb advice by zdas04, you should carefully consider the magnitude of accuracy that you truly require and the costs that you are willing or able to endure to accomplish your needs. You may want to consider how effectively you can use other available process or system data to cross-check the flow rate in question without incurring the problems and costs of additional testing or instrumentation.
Valuable advice from a professor many years ago: First, design for graceful failure. Everything we build will eventually fail, so we must strive to avoid injuries or secondary damage when that failure occurs. Only then can practicality and economics be properly considered.