bjr,
For 2-D flat slab analysis for vertical gravity loadings I use the "equivalent frame method" (Ref ACI 318) where the column stiffness and the stiffness of the transverse torsional member is summed via their inverse to give an "equivalent column stiffness". I usually do a full length 2D frame with full column height above (fixed at far end) and full column height below (fixed at far end, unless it is the foundation level and i may pin it).
Having said that, i occasionally use the net column stiffness, or sometimes the "enhanced column stiffness" to account for the infinite stiffness of the column over the slab/beam depth.
The variation between all 3 methods is seldom very large, for "typical" arrangements, so basically you can use any "rational" approach.
At end columns i usually reduce the column stiffness substantially as it is difficult to develop the calculated moments, and it they are indeed not developed the first interior span will have increased positive moments and deflections.
HTH