More eye drops can be dangerous 1

[enginesrus]

In all the years of manufacturing eye drops, what is the failure here? And why now with in the last 3 years? Most eye wash has boric acid ?

https://www.cbsnews.com/news/eye-dr...ne-bacteria-contamination-dr-bernes-ligheyez/

Also this was some years ago, another failure. Since when did our city water treatment stop? There is zero excuse for a
brain eating amoeba existing in a city water supply.

https://www.seattletimes.com/seattl...n-leave-doctors-bracing-for-possible-repeats/

In the old days we'd turn on the tap and the water had a chlorine smell to it, now the city water just allows black mold to grow?
Just curious why?

 

[SWComposites]

people don’t like to pay taxes??

 

[3DDave]

In Flint they cut back on anti-corrosives, allowing the thin layer protecting the iron pipes to dissolve. This allowed chlorine to react with the iron, depleting the chlorine and allowing microbial growth.

As the article suggests, more periods of warm weather have allowed tropical diseases to move farther north. This mainly affects ecosystems, such as when insects that are killed by cold winters are allowed to survive by warm winters allowing less ability for forests to recover.

 

[TugboatEng]

As the article suggests, more periods of warm weather have allowed tropical diseases to move farther north.

And that's a load of... Balamuthia has worldwide distribution.

https://www.cdc.gov/parasites/balam...eely in,potential entry point for Balamuthia.

Engine's, do you want chlorinated tap water? Sensationalizing one death out of 330 million in USA is how you get chlorinated tap water.

 

[3DDave]

Sorry Tug, there you are with a fresh pot of denial on the stove.

Increased temps don't cause parthenogenesis, but they do increase the populations which increase the chances and therefore the frequency of events. In the melting permafrost are bacteria and other small lifeforms that have been isolated for tens of thousands of years and are being released back into the environment. So, just because something is "worldwide" doesn't mean it isn't now flourishing in the warmer temperatures.

Virtually all public tap water is chlorinated.

 

[TugboatEng]

If the pathogen didn't kill us then it won't kill us now. The bugs hidden in the ice are nothing to worry about. It's just more clickbait.

Innate immunity is a thing.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536550/

 

[3DDave]

Sure, just like sickle cell trait protects against malaria, explaining why every human group gets sickle cell anemia. /s

If your ancestors didn't migrate across the now frozen tundra 20,000 years ago then you will inherit no resistance that developed in those who did.

 

[TugboatEng]

20k years ago much more of the earth was frozen. Sea levels were 300 feet lower than present levels because so much was frozen. Pathogens hidden in the ice are likely much more ancient and not likely to be pathogenic to modern humans or other species. If what you were saying were true, every ice core would require BSL-4 handling. You have bought into the clickbait.

 

[enginesrus]

So if these eye drop manufactures would at least use silver that should eliminate most of the problems.

 

[TugboatEng]

In the eyedrops case the recall is primarily due to the unapproved drug MSM. Adding silver isn't going to remove the unapproved drug.

 

[3DDave]

https://www.fda.gov/drugs/drug-safe...rtain-methylsulfonylmethane-msm-eye-drops-due

FDA is warning consumers not to purchase and to immediately stop using Dr. Berne’s MSM Drops 5% Solution and LightEyez MSM Eye Drops – Eye Repair due to bacterial contamination, fungal contamination, or both.
...
FDA conducted sampling and testing based on these products’ intended use in the eyes, and due to the industry’s recent manufacturing issues with eye drops. FDA’s testing showed the products were contaminated with microbes and were not sterile. Under the Federal Food, Drug and Cosmetic Act, eye drops must be sterile to be safe for use. The table below includes examples of specific microbes isolated from FDA testing.

Not having microbes would deal with the main problem.

Edit: See also

https://en.wikipedia.org/wiki/Methylsulfonylmethane

 

[TugboatEng]

3DDave, read the article more closely. It claims a do not buy warning was issued but then proceeds to describe it as a recall. It's an extremely poorly written article and seems to conflate two separate issues between two separate entities.

 

[waross]

Nice job of selective reporting Dave.
To get to the paragraph in the lower part of your quote, you had to skip over this paragraph.

The Dr. Berne’s and LightEyez eye drop products also contain methylsulfonylmethane (MSM) as an active ingredient. These products are unapproved drugs and illegally marketed in the U.S. There are no legally marketed ophthalmic drugs that contain MSM as an active ingredient.

--------------------
Ohm's law
Not just a good idea;
It's the LAW!

 

[3DDave]

The question was the reason for the recall - which is ONLY microbial contamination.

It is not selective to ignore factors unrelated to the recall.

Title of the recall:

FDA warns consumers not to purchase or use certain methylsulfonylmethane (MSM) eye drops due to contamination

Many products contain MSM; it isn't particularly dangerous, but bacteria and fungi are.

They aren't recalled for containing MSM.

 

[1503-44]

Seems clear that the reporter made an additional wrong association, but then again, journalists today can't hardly write any coherent full sentence.

--Einstein gave the same test to students every year. When asked why he would do something like that, "Because the answers had changed."

 

[DanKile]

Methylsulfonylmethane is generally regarded as safe in its intended use as a food additive.
FDA GRAS Notice
The FDA hasn't approved MSM's use as a drug, so the FDA deems it illegal to sell it as a drug.

The main reason for the recall is the bacteria/fungi contamination.

 

[drwebb]

Back to the original questions- there is not enough information in the popular press reports to indicate a detailed root cause. "In all the years of manufacturing eye drops" there have in fact been multiple cases of nonsterile or contaminated eye products being sold, (which the article references), so this is not really a new problem. The engineering controls for sterile manufacture are well-established, but depend on robust systems, good training and attention to detail, any or all of which operations focused on lowest costs may be challenged to consistently meet. Given that the affected products are designed and marketed containing unapproved/technically illegal ingredients for their intended application seems indicative of glaring inattention to details in product compliance, so perhaps not unexpected to exhibit symptoms of same in manufacture quality.

 

[IRstuff]

Sometimes, it boils down to complacency; you start a brand-new process and have a bunch in-process testing to make sure everything is clean, but over time, all these negative results cause management to ask why they're spending money to test something that NEVER fails. THAT's when trouble often starts.

TTFN (ta ta for now)
I can do absolutely anything. I'm an expert!

https://www.youtube.com/watch?v=BKorP55Aqvg

faq731-376 forum1529 Entire Forum list

http://www.eng-tips.com/forumlist.cfm

 

[3DDave]

It reminds me of the baby formula factory shutdown.