Yes, skew is a huge problem if not controlled, because when the bridge skews, the wheels run up against the rails and increase the friction, often dramatically. Then in my experience, it's VERY difficult to control skew if the motors are mismatched (as they now are). I've tried it with VFDs and had to resort to long range laser sensors to measure the distances between corners (because as the bridge becomes a parallelogram, the corners are no longer equidistant), then feed the delta into a PID loop controlling the VFD speeds to try to keep it straight. Very complex, very expensive, it would have been much much cheaper to just replace both motors with a matched set every time one went bad... but that wasn't my decision, I just implemented it.
Or it's the reverse rotation issue, that one would be kind of funny...
" We are all here on earth to help others; what on earth the others are here for I don't know." -- W. H. Auden