The 52 is an unpressurized liquid secondary seal. The 74 is a dual pressurized (gas) seal.
The plan 74 will always leak the buffer gas into the process and atmosphere, as the between seal space is maintained at a higher pressure than process. Depending on your tolerance for gas (nitrogen, CO2, air, whatever), the plan 74 is quite tolerant to cavitation, low VP margin, air entrainment, or other off-design conditions for a pump.
The plan 52 can be as simple as an atmospheric pot with oil and as complicated as a cooled reservoir with instrumentation and a pumping ring in the seals. In my facility, our amine pumps (rich and lean) are plan 52s. The lubricity of amine isn't great as ciise pointed out, but with adequate cooling the seals have fared well.
If your process is a condensing fluid, you'll need to monitor the collection of process into the barrier fluid in the pot. This can cause problems with environmental leakage past the secondary seal.
In any case, be aware of using Viton or any other similar material for O-rings in amine service as they will fail due to embrittlement. I would suggest Kalrez or similar material.