biofriend
Bioengineer
- Sep 17, 2008
- 25
I want to simulate the suction of a cell into a pipette
My model consists of a analytical rigid pipette and a spherical cell modeled axisymmetrically :
Properties : Viscoelastic (SLS)
Interaction :
frictionless
Hard contact
1- If I want to exert the instantaneous pressure I will face sever element distortion that even ALE adaptive meshing hardly can take care of it and also cell penetrates the pipette(although mesh is very fine in its neighborhood and hard contact is chosen) and if I don’t want to exert instantaneous pressure then I can’t see the elastic jump of the cell into pipette(which occurs upon instant suction pressure)and even in a non-instantaneous (ramp) pressure the cell still penetrates the master instance(pipette) which causes the process to fail.
In the case of sudden pressure or pressures with a sever ramp it seems that the cell is too soft for this magnitude of pressure because the deformation and length of cell penetrated in the pipette is far more than it should be and then after a while the job will be failed without success but I am sure that the constants are ok.
2-I have partitioned the cell edge in the opening of the pipette to exert pressure, and I know that the boundary of pressure is changed as the cell is sucked in. Is there any way to introduce the pressure not on the cell surface but in pipette? I mean so that we define a pressure be in the pipette and be exerted on whatever is located in it or near its opening like a sucking pipe?
Links to photos that may help to have a schematic imagination of the model:
1-
2-
I would be more than very grateful for your help,
Yours Sincerely,
Amir
My model consists of a analytical rigid pipette and a spherical cell modeled axisymmetrically :
Properties : Viscoelastic (SLS)
Interaction :
frictionless
Hard contact
1- If I want to exert the instantaneous pressure I will face sever element distortion that even ALE adaptive meshing hardly can take care of it and also cell penetrates the pipette(although mesh is very fine in its neighborhood and hard contact is chosen) and if I don’t want to exert instantaneous pressure then I can’t see the elastic jump of the cell into pipette(which occurs upon instant suction pressure)and even in a non-instantaneous (ramp) pressure the cell still penetrates the master instance(pipette) which causes the process to fail.
In the case of sudden pressure or pressures with a sever ramp it seems that the cell is too soft for this magnitude of pressure because the deformation and length of cell penetrated in the pipette is far more than it should be and then after a while the job will be failed without success but I am sure that the constants are ok.
2-I have partitioned the cell edge in the opening of the pipette to exert pressure, and I know that the boundary of pressure is changed as the cell is sucked in. Is there any way to introduce the pressure not on the cell surface but in pipette? I mean so that we define a pressure be in the pipette and be exerted on whatever is located in it or near its opening like a sucking pipe?
Links to photos that may help to have a schematic imagination of the model:
1-
2-
I would be more than very grateful for your help,
Yours Sincerely,
Amir