The simplest method to size a transformer is adding all none coincident loads that will run continuous such as motor load, lighting, heating, computers and miscellaneous loads. Use your engineering judgment to provide additional capacity margin (typ. 25%) to account for uncertainties and future growth.
For a water treatment plant, the motor load probably is the larger among all other loads. An estimate motor load could be determined considering the horsepower, power factor, pump and other equipment efficiency.
Probably a good idea is to have a least a redundant transformer connected to different sources and split the load evenly under normal conditions. One transformer should be capable to run the entire plant without overheating.