TiCl4
Chemical
- May 1, 2019
- 631
I am working with some of our lab folks on development of a process. Some of the chemistry is still in flux, but we are creating a heavy component that will be mixed in with a solvent (THF or similar) and water (it is soluble in both). I need to eliminate the solvent from the mixture to isolate all of the component in the aqueous phase.
Since the solvent is the low-boiler here, my first thought was distillation. The heavy component has negligible vapor pressure, so yield should not be an issue. The solvent and water mixture may still form an azeotrope, depending on how the third component affects the equilibrium curve.
I’ve never done any determination of equilibrium curves or interaction parameters before in a lab setting, so I was hoping someone could point me to a good reference for that and scaling distillation processes. If you have any other separation ideas as well, I’d like to hear them.
Since the solvent is the low-boiler here, my first thought was distillation. The heavy component has negligible vapor pressure, so yield should not be an issue. The solvent and water mixture may still form an azeotrope, depending on how the third component affects the equilibrium curve.
I’ve never done any determination of equilibrium curves or interaction parameters before in a lab setting, so I was hoping someone could point me to a good reference for that and scaling distillation processes. If you have any other separation ideas as well, I’d like to hear them.