Hi gordo,
The minimum axial load you need to generate on your gland during tightening is that given by the fluid pressure multiplied by the cylinder cross-sectional area acting within the cylinder bore. Example - if your bore is 3 inches and your pressure is 2750 lbs/sq in then your axial force is 19429 approx.
If you put this into your earlier equation T = KDP this should give you the minimum torque your gland requires. Obviously if there are any other forces acting on the gland they will also have to be taken into account.
With the axial force I calculated earlier, you should be able to work out the shear stress on the threaded portion and also calculate the tensile stress on the root diameter of the gland.
You can use the formulas in the link I posted earlier to determine whether the internal or external threads are overstressed.
The O-ring acts as a radial seal and therefore sealing is independent of gland tightening torque. If you wish to calculate the expansion of the cylinder bore due to the pressure then I would look in a text book for Lam'es equations which deals with pressure vessels.
The only time that leakage will occur between the gland and the cylinder bore is if the O-ring seal cannot compensate for the expansion of the cylinder bore. If this is already a tried and tested product then you have no need to worry about leakage.
Going back to my earlier comment about engaging the screw thread before the O-ring seal is seated in the bore, the point I am trying to make is, having assembled the O-ring onto the gland and inserting the gland into the cylinder bore, it appears from your diagram that the screw thread will engage before the seal is in the correct position ie, this means that to get the O-ring into the cylinder bore you have to screw the gland into place.
In doing this, this means that you have to screw the O-ring down into the tapered portion of the cylinder bore and finally into the reduced cylinder bore where it starts its job as a seal.
Because threads are not the best thing for aligning two components, it means that you could possibly damage the seal whilst screwing the gland into place. It would be better in my opinion if the O-ring groove was moved axially further away from the screw thread so when you offer the gland into the barrel the O-ring seal has already passed the tapered section and is sat in the final bore before you tighten the gland up.
Regards,
desertfox