Regulatory bodies typically will not accept only an automated system as the critical safety protection device for pressure vessels. Since you are concerned with a temperature excursion resulting in the vessel exceeding the pressure rating, a self-initiated pressure relief device will be required.
The key to the cyclone application is the suspended particle sizes, the air volume handled during the 3 seconds,and the dP across the cyclone. If you are concerned about separation efficiency during pressure ramp up to full flow due to vortex formation, proper sizing of the cyclone, placing two...