No there is no additional danger in using 600V vs 480V in hazardous areas. Once you go over about 10V, the difference in voltage is irrelevant in terms of ignition.
Bottom line, if you are in Canada, 600V is OK because there are a lot of other 600V users there. If you are in most of the US, it will be problematic in terms of finding motors, drives, lighting fixtures etc. In fact with lighting, using a 480Y277V 4 wire system has advantages in that you can use 1 phase to neutral for much of your lighting equipment because lots of manufacturers provide 277V ballasts. With 600V, you need to buy a transformer to run your lighting systems in most cases, and transformers cost money plus drop efficiency. There are a few ballast manufacturers now selling 347V ballasts in the US, but again, limited options.