Several years ago we had a customer who ran a fleet of HAZMAT waste disposal trucks in SoCal. He tried running recovered acetone as an addmix to his fuel. The treatment and cleanliness didn't appear to be an issue. His fleet was a 50/50 mix of CAT and Cummins, while running the mixed fuel at a blend of 95/5 diesel/acetone he had about a 90% engine failure rate in a four month period.
Most failures were in the fuel injection pumps, scuffing of the plunger to barrels mostly. Also experienced several problems associated with the acetone boiling off at normal engine out fuel temps, causing bubbles and in some cases leaks and other problems, mostly hard starting and stalling. Plus as mentioned above, a great solvent, lots of primary and secondary filter plugging initially as the acetone broke loose all the crud deposited in the tank and fuel system. Even on "well maintained" trucks (actually they were very well maintained and the customer's fleet manager was a technically smart guy).
Sounded like a good idea, seemed technically feasible, in the end it caused him a lot of problems.
We also in the course of this did some cursory emissions measurements with a Testo 350 and opacity meter, CO was down, visible smoke reduced, NOx up about 8-12%.
Would think with newer high pressure fuel systems this might even be a bigger problem.
Hope that helps