Simple answer: I am not sure.
But if I were to do it, I,
most definitely, would not waste time on making the
best geometry and the
ideal mesh. Why? One of the reasons is that there are other inputs (like stress-strain curves of bones, cartilage, ligaments, etc. or stress-time or strain-time curves of each of these tissues, loading conditions, boundary conditions, etc.) whose variations will have a big impact on the results anyway! One of your inputs may be accurate to the sixth decimal place, but if the other inputs are only accurate to the first decimal, your results too are going to be accurate to the first decimal!
So, as long as, there are no clear demonstrated downsides to tet mesh in a specific problem, I do not buy the hex mesh dogma anymore.
Take a look at this
link. One thing is for sure that a more complicated tissue geometry under impact was studied and the conclusion is precisely what I've been suggesting.
For a general meshing overview, take a look at this
link.
To me, the same is true for CT-based geometries. Almost always, one does NOT want a model so specific whose results are valid for one subject (in your case, one horse!) A good theoretical model is supposed to be as simple and as general as possible. Once the model is verified and validated (after a mesh convergence study), then one must perform sensitivity studies (material, shape, etc.).
Take a look at
this example. One can even import a few CT scans in to SolidWorks and make an excellent geometry if it is such a huge concern!