It depends if you are using features on the units with the DECS 250N that the DECS 200 does not have. The attached is a publication by Basler to upgrade a DECS 200 to a DECS 250, and describes the features, mounting and wiring differences.
The main differences between the two are,
DECS 250 has a load (VAR) share feature that the DECS 200 did not have.
The DECS 250 has some additional communication protocols available.
DECS 250N has a negative field forcing feature.
I have done several DECS 200 upgrades to DECS 250, but none backward. Knowing both AVR's unless you're using a feature in the units that isn't supported by the DECS 200, it should work fine.
Hope that helps, MikeL.