Ideally, if you could get everything right, every part would reach end of life at the the same time, and the engine would just turn to dust when its time is up. As a practical matter, parts have unequal lives, but whatever goes out first frags everything else, so it may not be easy to figure out the sequence of events.
Every time someone figures that out, and figures out how to prevent the failure, he goes into business. ... and probably loses his shirt, but the guy who figures out how to make the improved part at a profit, prospers, until the next revolution comes along.
The last major step change was replacing valve springs with something that's called pneumatic, and I think relies on pressurized nitrogen instead of wire in torsion.
Mike Halloran
Pembroke Pines, FL, USA