There's no theoretical reason you couldn't make a hollow valve ball. If you're that severely weight- constrained, you might consider a butterfly valve instead.
Given that nobody stocks ball valves like that, it's custom, and the wall can be as thin as you want it. ... remembering that you'll be paying for machining time.
If you want to make it really thin, you need to consider the forces from the valve seats and the stem in addition to pressure considerations. Some seats apply a lot of force and/or expect the ball to not deflect much.
Mike Halloran
Pembroke Pines, FL, USA