I think you need to deal with the problems caused by JT , and as indicated earlier in cannot be prevented.
If the valve is a single stage pressure reducing valve, then there will be an extreme JT effect at the "vena contracta" and this may cause condensation of liquids ( or even solids in the case of some gases ,such as CO2) , and the later flashing of these liquids downstream of the vena contracta can cause erosion/ corrosion . This particular problem might be addressed by using a multistage valve, such as a CCI self-drag valve.
If condensation will occur nonetheless, then you would need to add drain pots or separators to remove the liquids that are condensed- similar issues happen in natural gas pipelines as the product is delivered to the comsumer's lower pressure gate.
And finally, you can in theory get power out of the pressure reducing station if the valve is replaced with a turbine, but the JT effect would then be greatly magnified. The power turbine can be synched to the grid using modern solid state electronics, as used at Capstone micro-turbines or at wind turbines.
"Whom the gods would destroy, they first make mad "