1) make sure that you are running a driver that is supporting your device, i have recent experience that a "too new" driver did not work with a old spacemouse.- We downloaded a matching legacy driver from 3D connexion and it worked as expected again.
2) there are 3 windows variables setting where the 3dconnexion software is located, check that these contains "some files" ...
Regards,
Tomas
The more you know about a subject, the more you know how little you know about that subject.