If, In fact, you have 300 psi water (solution) at the point where the pipe arrives at the column, you will have cavitation, unless the temperature of the solution is such that its vapor pressure is higher than the atmospheric pressure in the column. It's hard to say with confidence since you have not stated flowrate, temperature and the true composition of the solution, but I suspect strongly that a globe control valve with a single-stage anticavitation cage would be appropriate for the application. If the solution is hot and it's Flashing, an eccentric rotary plug valve with the seat on the downstream side would be a viable choice.
Look at the architecture of the column and verify that the nozzle is not directed at something expensive and/or difficult to repair. You want the 2-phase flow to go in to free volume so it can slow by friction instead of by impacting upon a target.