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Seeking Guidance on Developing an Adhesive Coating Formula

renatab

Bioengineer
Mar 29, 2025
2
Hello,

I’m working on creating a thin, flexible adhesive coating that can stick to moist surfaces (such as the inside of the mouth) and stay in place for several hours without dissolving or breaking down. The coating also needs to:

  1. Prevent friction or tearing, making it difficult to bite through
  2. Be biocompatible and safe for oral use
  3. Be resistant to saliva and moisture
  4. Remain flexible to move with soft tissue without cracking
  5. Apply as a thin, smooth layer
I’m looking for suggestions on base materials, adhesives, and formulation techniques that could meet these criteria. Any insights on film-forming agents, polymers, or barrier materials that offer durability and flexibility in a wet environment would be greatly appreciated.

Thank you for your time and expertise!
 
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Thank you for sharing this! It's truly fascinating but still in the research phase from what I see. Do you know of any similar commercially available adhesives?
 

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