In retrofit engineering, you still need to design to either the code as it exists today, or the code as it existed when the plant was built, both of which requre analysis of the system to ensure it is capable of accepting the loads present. Which one is really down to agreement between you and the client and the differences between now and then as it is often difficult to "ring fence" changes in code within a plant. I am surprised that the refinery doesn't have policies and standards / specifications for modifications as there will probably have been onfgoing since it started work some 40 years ago....
Sections in B 31.3 are part 5, sections 319 to 322.
The actual impact is dependant on your actual design and piping configuration, but you're potentially adding some significant weight and mods to the piping in order to squeeze two more valves in which will probably have an impact on the systems, including the original process pipework and the vent pipework. Sounds like you don't want to do the analysis but without doing at least one or two "worst cases" it is very diffiuclt to prove a negative. If you pick two or three out which look like they could have the biggest impact, study / analyses those and then make your decision, at least you have some proper data to use. Probably not what you wanted to hear, but many incidents have been caused by retrofit engineering occurring piecemeal and everyone being able to justify not doing things until the cumulative effect overwhelms the, probably quite corroded, strength of the system.
My motto: Learn something new every day
Also: There's usually a good reason why everyone does it that way