You mean Orbix 6.3.3 ? No we tested with 6.3.2 that comes with I-Deas 6.3, we don't use I-Deas 6.4/6.5
TDI wizard doesn't understand Win10 networking, it won't browse for the Team directory network share. Easily worked around by configuring I-Deas startup manually using the oldskool IDEASOGL.cmd & setup_varbs.cmd
NX I-deas is officially certified and supported on Windows 10 starting last year with the release of NX I-deas 6.6. In fact, that was the main reason for that Release.
See SFB-IDEAS-11239 for more details.
During testing, we found some issues where some commands, scriptings, and such required elevated permission (i.e. Run as Admin) due to extra Win 10 security, but was not clear if that was due to settings from Siemens IT on the test machines or if customers will also encounter that. There are notes to this effect in the README, noting all caveats we found on Win 10.
My personal observation is it appears needed for operations that turn around and interact with other system files (e.g. TDI, some OI scripts, dmadmin,...), to make sure they are not security violations.