In addition to thermal loads, a tank nozzle will be subjected to:
1. Rotation due to bulge, worst in the lower courses.
2. The effects of settlement and ground compression under filling / emptying.
These may be quite significant problem areas dependent upon the tank size.
Also, defining a tank nozzle as an anchor ... i.e., rotationally fixed would be very conservative, since there will actually be significant flexibility. This can be addressed using data from API 650.
IMHO, the best solution to most large tank connections at a low elevation is a double-tied bellows at the nozzle.