It's unclear what you're asking.
That weld has to be designed for a few things:
-Shear flow this ensures tension and compression get into the flanges for composite bending action between the elements
-Transfer of loads between elements at load application points if there isn't a prepared bearing load path or stiffeners that do the same thing. If you have a point load on the beam from above, this needs to get into the web somehow. If you have a bearing point below, the load needs to get out of the web and out of the beam somehow. Usually this is pretty straightforward, but it depends on what kinds of loads are happening
-Sufficient connectivity between elements so that any buckling modes are of the whole section rather than independent elements and that other weird failure mechanisms don't happen. This is usually covered by dimensional minimums in the codes, but you don't want the compression flange buckling in it's weak axis or the web starting to act in bending because you have welds every five feet.
If you're talking about welding stresses induced by the welding, this can be ignored in most conditions.
I'm assuming this is all covered in AISC but haven't ever done a US Plate Girder. In Canada the clause is:
"14.2.3 Fasteners or welds connecting flanges to webs shall be proportioned to resist horizontal shear forces due to bending combined with any loads that are transmitted from the flange to the web other than by direct bearing. Spacing of fasteners or intermittent welds in general shall be in proportion to the intensity of the shear force and shall not exceed the maximum for compression or tension members, as applicable, in accordance with Clause 19"
Clause 19 has a bunch of dimensional minimums and criteria for general built up sections.