Thanks all the reply.
It seem no project in practice of without antifreeze in 1 degree C chilled water loop. From point of safety design, it should has antifreeze in lower temperature water loop design.
The glycol chiller and AHU use heat exchanger to separate glycol water loop and chilled water loop, so glycol chiller loop will has antifreeze to prevent ice-built.
Assumption propylene glycol antifreeze in water, in worst case, water leakage of cooling coil will make it through air to contact with oral pharmaceutical product. That’s the reason why the 1 degree C water without any antifreeze I want to design. Is it possible to use suitable component in...
I'm trying to use water medium instead of glycol in waterside of cooling coil due to it is not sure if any impact of glycol to the air side. Does it work for using a heat exchanger to provide 1.5 degree C chilled water for low temperature dewpoint coil loop design without glycol added?
There is the question about water side of HVAC system. I plan to use a 1 degree c chilled water loop to keep coil's LAT of AHU at 4.5 degree c. Is there any concern of 1 degree c water loop design?