cef3rd,
I assume you're trying to estimate the airflow vs pressure curve through a power supply.
Most accurate is to test or model the new power supply, of course, but if you can estimate the change in open area you can get a rough resistance curve. Not sure I can explain it very well via email but I'll try:
Look down the tested power supply in the direction of airflow. "Open area" is the unobstructed area available for airflow (WxH minus obstructed area). Since the open area can change dramatically along the depth, choose the cross-section with the lowest open area (often this occurs at a vent shared with the power receptacle, etc).
Next, estimate the open area for the new supply.
At a given volume flow (CFM), the velocity change is the inverse of the area change (ie, if open area is cut in half, velocity doubles).
For turbulent flow, pressure is proportional to velocity squared. You can use this to estimate the new pressure curve (ie, if open area is cut in half, velocity doubles and pressure increases by a factor of four).
Good luck,
ko (