JackTrades,
Unless you have an extremely stable job waiting on you here: I wouldn't even consider it. The local large firms seem to be set on self-destruct and are not of good quality (more on that in a moment). All told, they have spit nearly 500 people out on the street over the last year (and 300 more are coming from what I hear). I had lunch with my former boss the other day and he told me he furloughed himself for the month of July. [He laid me off at the beginning of May, and I haven't worked since. The only reason I haven't relocated is because I'm taking a shot at the SE II next month.]
As for my background, I have lived/worked in Greenville for 12 years (as a structural engineer). I was a (discipline) lead engineer at my previous company, I have an MS & BS and am registered in 7 states. And even with all that: I couldn't get arrested at an engineering firm in this town right now.
But it runs even deeper than that (i.e. my reason for wanting to relocate). Even if things were roaring: I'm still deeply disturbed by what I have seen at some of these [local] companies. [In fact, I felt this way before the recession.] There seems to be a lack of a commitment to quality (and quality people). Let me give you a couple of examples. There is this guy I know [we'll call him Mr.X for the sake of conversation]. Mr. X graduated Magna cum laude (with both his MS & BS degrees, if I remember correctly) and he was an SE [registered in Illinois, et al] before he was even 30 years old (and in this area, meeting someone with those credentials is right up there with seeing Bigfoot). He's really not even a close friend of mine (we're friendly but we don't talk that much) and I have made it a point to mention him to every department head everywhere I've worked. Their reaction? Disinterest. Incredible. What kind of idiot would let that kind of talent pass them by? They could have gotten him but it's too late now (as he is a partner at a small firm at this point). An example on the other end: Mrs. Y. This lady has to be one of the most pathetic engineers I have ever met in my life. Mrs. Y is nearly 30 years into her career and isn't even registered, has no technical prowess to speak of, and can't even do CAD. I remember I had a big confrontation with her [when I worked with her] because of a STAAD model she did for me of a cast in place, R/C frame where she didn't even use cracked section properties or member offsets (as well as a myriad of other errors). And she seems to have no problem hanging on to her job. What I suspect is happening here is 2 things: the desire for low-cost people (bereft of creds/skills), and nepotism gone wild (as Mrs. Y has a husband that is a heavy hitter where she works). At some point the issue has to become: can this guy/gal execute the work that is in front of them? And that starts with a commitment to good people. The management of these companies have the idea that people are a dime a dozen. GOOD people are not.
Granted you could probably find organizations like that anywhere. But this town is packed with them. And I have had department heads (and other higher ups) admit to me that as far as the company's management is concerned: the Greenville office(s) is a standalone job shop (i.e. it will stay open as long as they can find work to sustain themselves, and there is no long-term plan as far as personnel goes (which explains why I have been one of the few people under the age of 50 working at these places)).
So in short: no, I wouldn't recommend this area to anyone (engineering wise). I've lived here my whole life (I grew up in a neighboring county), love the weather and am close to my family (who live here as well) and have pretty much washed my hands of this whole deal.
My 2 cents.