Whenever a choice has to be made for a part which undergoes cyclic stresses designer prefers machined or forged component over a cast one. This is because he has less confidence on a cast part due to its inherent limitations. Hence he applies a safety factor ranging from 4-5 for a casting,making the part heavier.
There is a thinking to reduce the factor to 2 or 3. Using the fracture mechanics route a critical flaw size is defined. However the existing NDT techniques are unable to recognize the flaws when they are 10mm (indicative) and below making the choice difficult.
Additionally say in case of steel casting the inhomogeneities are large, there is grain size variation due to differences in cooling rate across sections,segregation and improper response to heat treatment add to difficulties. Finally we have the residual stresses in the castings making the choice of steel casting for varying loads very difficult.
However, I have been making parts for hydro electric machines like runner blades,pelton wheel,buckets,guide vanes stay vanes,pulp refiner plates,slurry pump and process pump impellers shot blasting machine blades,etc as castings. These are profiles difficult to process by machining or forging,.
I feel,the process controls and integrity of steel castings need to be improved before they are accepted by designers.
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"It's better to die standing than live your whole life on the knees" by Peter Mayle in his book A Good Year